A paracetamol tablet
won't hurt
you; it will alleviate
your aches.
That white tablet’ll
move down
your GIT and swiftly
disintegrate.
Within an hour, it’ll
virtually all
be absorbed into the
bloodstream.
The [paracetamol]-
time plot will
reach its max
then
drop by half-
lives.
The area under
the
curve will
then
capture the drug’s
kinetics.
Particles will’ve gone
through fine
branches straight into
most tissues.
This paracetamol
won't hurt
you; it will alleviate
your aches.
It will metabolise
in your liver
to produce inactive
metabolites.
The chemicals will
move between
two compartments:
blood & urine.
The [metabolite]-
time plot will
reach its max
then
drop by half-
lives.
The area under
the
curve will
then
capture metabolic
kinetics.
Within a day, it’ll
virtually all
be excreted via the
urinary tract.
There will be nary
a trace of the
paracetamol left in
your system.
Your pain will’ve
become
a distant memory.
The Pharmacokinetics of Paracetamol
By Michael Leach | 1 November 2017